Artificial Organs & Measurement Systems

The research group combines engineering and medicine with the goal of translating innovative technical concepts into clinically applicable solutions. The focus is on fluid mechanics in medicine, particularly the analysis, simulation, and optimization of complex fluid dynamics in biological and technical systems.

Against this backdrop, we develop and validate artificial organs as well as novel measurement and sensor systems that enable the precise monitoring and control of physiological processes. Using experimental test beds, numerical flow simulations, and modern design methods, we guide the process from the initial idea through prototyping to clinical application.

The research group builds on the long-standing expertise of the Laboratory for Biofluid Mechanics, founded in 1985 at the Virchow Clinic, and combines this with modern approaches to digital modeling and interdisciplinary translation.

Another area of research is the realistic modeling of biological fluids and the investigation of complex flow processes in medical systems. The goal is to reliably predict blood damage, thrombus risk, particle transport, and shear stress. The results form a central basis for the safe design of new medical technology.

Another area of focus is the development of portable, rapid, and non-invasive diagnostic systems for use at the patient’s bedside. The focus is on biosensors, nanoparticle-based detection methods, and telemedicine monitoring solutions. The goal is the early, digital, and decentralized detection of diseases.

Our translation projects focus on the development, simulation, and validation of medical devices and precise drug delivery systems. Particular emphasis is placed on safety, dosing accuracy, and the absence of material-related contamination. The systems are designed for future cell, gene, and implant therapies.

Our expertise encompasses physical and virtual test systems for realistic development, measurement, and validation of medical technology systems. We focus on physiological test benches, experimental measurement platforms, and coupled simulation environments. Our goal is to conduct early functional testing, optimization, and risk minimization of new medical devices.

In this area of research, our focus is on developing bioreactors with innovative fluid dynamics that can generate gradients of drug combinations. These bioreactors can be used to assess both the efficacy of the combinations and the development of evolutionary resistance.